Principal Investigators
Lead Principal Investigator and Director of Synergy
Chief Research Officer
Dartmouth Hitchcock Medical Center
Senior Associate Dean for Clinical & Translational Research
Professor of Emergency Medicine and of the Dartmouth Institute
Director, C. Everett Koop Institute
Geisel School of Medicine at Dartmouth
Dr. Bernstein arrived at Dartmouth in February 2021 as the inaugural Chief Research Officer at Dartmouth Hitchcock Medical Center and the Senior Associate Dean for Clinical and Translational Research at the Geisel School of Medicine at Dartmouth, Director, C. Everett Koop Institute, and Professor of Emergency Medicine at Geisel. His interests are in the treatment of tobacco dependence in various clinical settings, implementation science, and training junior investigators. He is also leading a team of investigators looking to return a Clinical and Translational Science Award (CTSA) institute to Dartmouth. He holds additional appointments in the Dartmouth Cancer Center, Dartmouth Center for Implementation Science, and The Dartmouth Institute.
Before coming to Dartmouth he was Professor of Emergency Medicine and Public Health at Yale and Vice Chair for Research in the Department of Emergency Medicine. Dr. Bernstein was the founding Director of the Yale Center for Implementation Science, directing K12 and T32 programs to train junior investigators in that field.
Dr. Bernstein pioneered the treatment of tobacco dependence in emergency department (ED) patients, and has identified specific pharmacologic and behavioral interventions that are efficacious. His current research focuses on optimizing the treatment of tobacco dependence in individuals with HIV/AIDS.
His work has been supported by the National Cancer Institute, National Heart, Lung, and Blood Institute, National Institute on Drug Abuse, Agency for Healthcare Research and Quality, the Centers for Disease Control and Prevention, the Robert Wood Johnson Foundation, and the American Legacy Foundation, among others. Dr. Bernstein has served in an advisory capacity developing tobacco policies and measures for groups including the National Cancer Institute, Centers for Medicare and Medicaid Services, the Joint Commission, and the National Committee for Quality Assurance.
Dr. Bernstein holds a bachelor’s degree from Princeton University and earned his medical degree from Temple University School of Medicine. He trained in residencies at SUNY Health Sciences Center in New York (Medicine) and at Long Island Jewish Medical Center (Emergency Medicine). Dr. Bernstein was a fellow in hematology-oncology at SUNY Health Sciences Center and a visiting fellow in clinical epidemiology at the Robert Wood Johnson Clinical Scholars Program at Yale.
Anna N. A. Tosteson, ScD
Principal Investigator
Director, Research Program
Professor of The Dartmouth Institute
Professor of Medicine
Professor of Community and Family Medicine
James J. Carroll 1948 Professor of Oncology
Geisel School of Medicine at Dartmouth
Anna Tosteson is the James J. Carroll Professor of Oncology and the Associate Director for Population Sciences at the Norris Cotton Cancer Center. She serves as an Associate Director for SYNERGY, Dartmouth’s Clinical and Translational Science Institute. She previously served as the Interim Director of The Dartmouth Institute for Health Policy & Clinical Practice.
Tosteson is a decision scientist and health services researcher who studies how the diffusion of innovations in health care are changing health, costs and quality of care. Through the use of diverse data sources including registries, clinical and epidemiological studies, and administrative claims data, she seeks insights into the long-term clinical and economic effects of alternative approaches to health care delivery with a focus on cancer screening and women’s health.
Tosteson is internationally recognized for demonstrating osteoporosis’s direct and indirect economic and societal costs on the health care system, workforce productivity, and quality of life. Her work on the surgeon general’s report, Bone Health and Osteoporosis, contributed to the adoption of prevention, screening, and treatment for that disease.
Tosteson earned an ScD in biostatistics (health decision science), an MS in biostatistics from Harvard University, and a BS in statistics and biometry from Cornell University.
Keith D. Paulsen, PhD
Principal Investigator
Robert A. Pritzker Professor of Biomedical Engineering, Thayer School of Engineering
Professor of Radiology & Surgery, Geisel School of Medicine
Scientific Director, Center for Surgical Innovation, Dartmouth-Health
Co-Director, Translational Engineering in Cancer Research Program, Dartmouth Cancer Center
Dr. Keith Paulsen, Ph.D., is the Robert A. Pritzker Professor of Biomedical Engineering at Dartmouth’s Thayer School of Engineering, and Professor of Radiology and Surgery at its Geisel School of Medicine; Director of the Advanced Imaging Center and Scientific Director of the Center for Surgical Innovation at Dartmouth Hitchcock Medical Center; Co-Director of Translational Engineering in Cancer at the Dartmouth Cancer Center.
Paulsen’s research interests are currently centered on imaging and image-guidance for the detection, diagnosis and treatment of diseases, especially cancers, in the brain, spine and breast. His research program continues to be highly translational in terms of moving innovative technologies, many of which are developed in house, into early stage clinical feasibility studies.
Paulsen is a Fellow of SPIE, AIMBE, IEEE, Optica, NAI, and Co-founder of start-ups Cairn Surgical and InSight Surgical Technologies. He has authored 500+ archival publications cited more than 38,000 times (h-index of 107), and is an inventor on 40+ issued/pending patents over the past 30 years. He earned his BS in Biomedical Engineering at Duke University, and his MS and PhD in Biomedical Engineering at Dartmouth College.
